Retrospective clinical study for advanced brain - gliomas by adjuvant electro - hyperthermia treatment

Gliomas are one of the most common primary brain-tumors. Despite surgery and radiotherapy (RT) with or without adjuvant chemotherapy, malignant glioma remains an almost uniformly fatal disease characterized by a rapid and devastating clinical course. Deep region hyperthermia (capacitative electro-hyperthermia) as an oncological treatment in brain-glioma (BG) is applied either alone or in combination with chemoand/or radiotherapy. We present a retrospective study of 140 patients, which were treated/followed from February 2000 to June 2005. The endpoint was the overall survival and the survival from the 1st oncological hyperthermia treatment (survival from the relapse untreatable by other methods). The median/mean survival times were 19.8/31.7 and 6.7/10.0 months from 1st diagnosis and from 1st hyperthermia, respectively. Results support the feasibility of capacitative deep region hyperthermia for advanced brain-glioma patients.